Skip to Main Content

Genomics, Genetics, & Epigenetics

The Genomics, Genetics, and Epigenetics (GGE) Program is a preeminent national and international hub for groundbreaking cancer genomic and genetic/epigenetic research that makes field-changing discoveries, develops impactful novel analytical tools, and translates these discoveries into new therapies and diagnostic tests.

In collaboration with the program leaders — Lajos Pusztai, MD, DPhil, Jeffrey Townsend PhD, and Qin Yan, PhD — members of the GGE program study gene alterations in cancer with the goal of translating this knowledge into new drugs, novel therapeutic strategies, and novel diagnostic tests.

  • Studies

    • The discovery of mutations in genes and DNA that cause cancer
    • Analysis of genomic changes and their functional consequences on gene expression
    • Characterization of mechanisms that control protein production from genes
    • Epigenetics
    • Protein structure
    • Analysis of large-scale genomic data
  • Goals

    • Identify and characterize the function of genetic alterations and epigenetic changes that contribute to cancer development and progression.
    • Develop new analytical tools, data resources, and novel laboratory models that enable better characterization and understanding of the cancer genome.
    • Translate genomic observations into clinically useful diagnostic and prognostic tests, and develop new therapies that exploit genetic and epigenetic alterations in cancer.